We look forward to connecting with you at the upcoming AACR Annual Meeting in Chicago from April 25–30! At GenoBioTX, we understand that robust, translationally relevant preclinical models are critical for confident decision-making in oncology drug development. We specialize in developing genetically modified and humanized mouse models that provide the insights necessary to effectively evaluate […]
The 2024 Nobel Prize in Physiology or Medicine has been announced, and the winners are two American scientists, Victor Ambros and Gary Ruvkun, in recognition of their discovery of microRNA and its role in post-transcriptional gene regulation. This discovery is considered a major breakthrough following the central dogma of molecular biology. The Nobel Committee stated […]
Cre-lox system, characterized by simple manipulation and high-efficiency recombinase, has been employed as a powerful tool of gene-editing. Application of Cre-lox system can achieve time-specific knock-out and knock-in of target genes in specified cells, tissues, and organisms, thereby regulating genes of interest spatiotemporally, which has profound impact on research of genetic function and animal modeling. […]
We provide gene editing techniques such as CRISPR/Cas9, transgenic approaches, or gene knockout strategies.
Researchers can request specific modifications to evaluate phenotypic changes, drug responses, or genetic interactions, facilitating the advancement of biomedical research and therapeutic developments.
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