Foxp3-IRES-DTR-2A-tdTomato(BALB/c)
Nomenclature
BALB/cAnSmoc-Foxp3em9(IRES-DTR-2A-tdTomato)Smoc
Cat. NO.
NM-KI-200213
Strain State
Embryo cryopreservation
Gene Summary
Gene Symbol
Foxp3
Model Description
Validation Data
CT 26 tumor cells were injected into FOXP3-DTR mice administered with different treatment, and Balb/c mice, respectively. And tumor growth curves of each group were recorded.
Fig 1. The growth of CT26 tumors in Foxp3-IRES-DTR-2A-tdTomato mice administered with different treatment and Balb/c mice. (In collaboration with CrownBio)
Proportion of different type-specific T cells and macrophages in peripheral blood of each group analyzed using FACS
Fig 2. The percentage of different type-specific T cells and macrophages in peripheral blood of CT26 tumor-bearing Foxp3-IRES-DTR-2A-tdTomato mice administered with different treatment and Balb/c mice is detected by FACS. (In collaboration with CrownBio)
Proportion of different type-specific T cells and macrophages in spleen and tumor of each group analyzed using FACS
Fig 3. The percentage of different type-specific T cells and macrophages in spleen and tumor of of CT26 tumor-bearing Foxp3-IRES-DTR-2A-tdTomato mice administered with different treatment and Balb/c mice is detected by FACS. (In collaboration with CrownBio)
Fig 4. DTR mediated cell knockout in spleen of Foxp3-DTR/tdTomato mice (BALB/c).
Fig 5. DTR mediated cell knockout in mesenteric lymph nodes of Foxp3-DTR/tdTomato mice(BALB/c).
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