Twist2-Cre

Background : C57BL/6Smoc

Catalog : NM-KI-200138

Strain Name : C57BL/6Smoc-Twist2em1(Cre-WPRE-polyA)Smoc

Gene Summary

Gene Name

Model Description

A Cre-WPRE-polyA expression cassette was knocked into the Twist2 gene start codon site via CRISPR/Cas9 mediated recombination.

Validation Data

Twist2-(Cre)-1.png

Fig.1 Cre-mediated recombination in the brain and intestine of Twist2Cre/+; Rosa26tdTomato/+ mouse. Detection of tdTomato (red) in the brain and intestine of Twist2Cre/+; Rosa26tdTomato/+  mouse.

Twist2-(Cre)-2.png

Fig.2  Detection of tdTomato (red) in various tissues of Twist2Cre/+; Rosa26tdTomato/+ mice. Cre-mediated recombination can be detected in the brain, but not in the cerebellum. Besides, tdTomato expression can also be observed in heart, liver, lung, submandibular gland, skin, muscle and stomach.

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