News Insights

Stay updated with our latest research breakthroughs, announcements, and insights.

News
1 min read

Live Ready-to-Use Models Now Available – No Wait Times!

GenoBioTX is pleased to announce the availability of ready-to-use knockout (KO), knock-in (KI), and overexpression models for preclinical research. With no wait times, researchers can now accelerate their studies using our live genetically engineered models, ensuring efficiency and reliability in critical research areas. Advancing Preclinical…
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Blogs
8 min read

The Hidden Killer in Chronic Kidney Disease – Alport Syndrome

Chronic kidney diseases are highly diverse, but among them, there is a type of chronic kidney disease that may start showing signs in childhood. However, early symptoms are often subtle, leading to neglect by parents or misdiagnosis by doctors, resulting in delayed treatment. Moreover, this…
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Webinars
2 min read

Personal Human lmmune System Mice: Accelerating the Translation of lmmuno-therapies from Bench to Bedside

Register Link: https://www.eventbrite.com/e/genobiotx-february-2025-webinar-tickets-1228646116609?aff=oddtdtcreator Date: Meet Our Speaker: Dr. Huang earned a Ph.D. in 2004 from the Institute of Zoology, Chinese Academy of Sciences, followed by a postdoctoral fellowship at Peking University Health Science Center (2004–2006). Dr. Huang has dedicated over 15 years to groundbreaking research…
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Promotions
1 min read

Fully Human Antibody Transgenic Mice Tailored to Your Antigen in 3 Months

Who We Are GenoBioTX is a well-known contract research organization (CRO) providing genetically engineered animal models, and preclinical drug discovery services to biopharmaceutical companies and life science researchers. Our Services Generate KO HOM mice in just 3 months Intergrated antibody discovery platform YouMabTM fully human…
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Blogs
4 min read

Why We Need Humanized Mice?

You may have come across accumulating reports uncovering biomedical breakthroughs which all use humanized mice in vivo assays. So, you may wonder, what is a humanized mouse and why is it so commonly used in biomedical research? Humanized mouse is generally referred to as a mouse has been xenotransplanted with human cells and/or engineered…
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Blogs
5 min read

Some Basics about Cre-lox and Inducible Cre in Mouse Modeling

Cre-lox system, characterized by simple manipulation and high-efficiency recombinase, has been employed as a powerful tool of gene-editing. Application of Cre-lox system can achieve time-specific knock-out and knock-in of target genes in specified cells, tissues, and organisms, thereby regulating genes of interest spatiotemporally, which has…
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Blogs
4 min read

How to Verify Your Cre-lox Model

Now that the genetically engineered mice that carry a Cre-conditional (“floxed”) allele in target gene are at your hand. And the mice are supposed to express Cre in target tissue. The validation of your Cre-lox model become very indispensable, so here we advise you of some essential steps. Genotype the mice…
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News
5 min read

These Mice Are About to Go Viral Because of the Nobel Prize!

The 2024 Nobel Prize in Physiology or Medicine has been announced, and the winners are two American scientists, Victor Ambros and Gary Ruvkun, in recognition of their discovery of microRNA and its role in post-transcriptional gene regulation. This discovery is considered a major breakthrough following…
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Webinars
2 min read

Enhancing Your Research: How GenoBioTX’s Gene Editing Technology Empowers Research Breakthroughs

Registration link: https://www.eventbrite.com/e/genobiotx-monthly-webinar-tickets-1053785844829 Date: Wednesday, Oct 30th, 2024; 11:00 am PDT, or 2:00 pm EDT Webinar Highlights: This seminar will introduce GenoBioTX’s gene editing platform and technology, highlighting how these techniques can enhance your research projects. We will cover the history of genome editing, provide an…
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Blogs
6 min read

Why IL-2 Still Holds Promise in Therapeutics of Cancer and Autoimmunity

Aclidineleukin (high-dose IL-2) is the first FDA-approved cancer immunotherapy for metastatic renal cell carcinoma (RCC) and melanoma, but the widespread clinical use of aclidinein has been limited by its short half-life, serious side effects, and simultaneous stimulation of Treg activation. With the breakthrough of studies…
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Webinars
2 min read

Overcome the Hurdle to Generate High Affinity and Diversity Antibodies to Self- or High Homology Antigens

Registration link:  https://us06web.zoom.us/webinar/register/WN_zp48kyBhSH2rHpm_adFNIw Date: Webinar Highlights: This webinar will explore various methods for generating monoclonal antibodies, emphasizing the challenges of producing high-affinity antibodies to self or highly homologous antigens. Traditional methods, like in vitro screening and hybridoma-derived antibodies post-immunization, are cost-effective but struggle with these…
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