Strain Model Specification

hCTLA-4/hCD28(BALB/c)

Strain Name BALB/cAnSmoc-Ctla4tm1(hCTLA4)Cd28tm1(hCD28)Smoc
Catalog Number NM-HU-200226
Genetic Background BALB/cAnSmoc
Synonyms Cd152, Ly-56, Ctla-4,
NCBI ID 12477, 12487 ↗
MGI ID 88556, 88327 ↗
Ensembl ID ENSMUSG00000026011, ENSMUSG00000026012 ↗
Strain State Sperm cryopreservation
Research Application Immunotherapy

Validation Data

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Fig1. Analysis of human CTLA4(hCD152) expression in the spleen by FACS . The homozygous KI mouse expresses human CTLA4 on T cells.

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Fig2. Analysis of human CD28 expression in the spleen by FACS . The homozygous KI mouse expresses human CD28 on T cells.