Strain Model Specification

Tnf-KO

Strain Name C57BL/6Smoc-Tnfem1Smoc
Catalog Number NM-KO-00100
Genetic Background C57BL/6Smoc
Gene Symbol Tnf
Synonyms DIF, TNF-a, TNF-alpha, TNFSF2, TNFalphaa, Tnfsf1a, Tnlg1f
NCBI ID 21926 ↗
MGI ID 104798 ↗
Ensembl ID ENSMUSG00000024401 ↗
Strain State Repository Live
Research Application Immune and cancer research

Validation Data

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Fig.1 Detection of TNF expression in spleen and thymus by RT-PCR. 

Wild type: only one band at 209 bp with primers F1/R1(mTnf). 

Abbr. M, DNA marker;  HO, homozygous; WT, wild type.

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Fig.2 Detection of mTnf expression in spleen and thymus by Q-PCR. 

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Fig.3 Detection of mTNF-a expression in serum by ELISA (male, 8wks, n=2). 

Abbr. HO, Homozygous; WT, wild type.

Note.TNF-KO and C57BL/6 mice were i.p. injected with LPS.