CCR8, as a novel immune checkpoint in tumor microenvironment, was hotly discussed during 2022 AACR conference. Since then, numerous prestigious pharmaceutical corporations have shifted their attention to CCR8, previously almost unknown. You may wonder why CCR8 gave rise to so strong interest of pharmaceutical industry. Just follow us to have a quick review of CCR8, […]
Now that the genetically engineered mice that carry a Cre-conditional (“floxed”) allele in target gene are at your hand. And the mice are supposed to express Cre in target tissue. The validation of your Cre-lox model become very indispensable, so here we advise you of some essential steps. Genotype the mice When unexpected phenotypes are observed during your working with mice, the […]
Join our webinar on July 25th for an introduction and background on humanized mouse models, focusing on their effective applications in preclinical research for advancing targeted therapies across diseases. Date: Thursday, July 25th, 2024; 2:00 pm EDT or 11:00 am PDT Webinar Highlights: Introduction to humanized mouse models for preclinical research developed by GenoBioTX Discover […]
We provide gene editing techniques such as CRISPR/Cas9, transgenic approaches, or gene knockout strategies.
Researchers can request specific modifications to evaluate phenotypic changes, drug responses, or genetic interactions, facilitating the advancement of biomedical research and therapeutic developments.
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