Customized Genetically Engineered Mouse Models

Combined with versatile technical platforms, SMOc guarantees every custom model created is intended to fulfill diversified requirements from researchers. We offer not only classic knockout and knockin models, but also conditional point mutations and conditional knockouts with reporters. Our custom models will be the cornerstone of your research

Comparison of three gene modification technologies

Technology
Key points
Duration
Applications
Pros and Cons
CRISPR/ Cas9
Cas9 nuclease cuts specific sites.
3-9 months
Gene knockout, conditional knockout, gene knock-in, point mutation, humanization.
CRISPR/ Cas9
Cas9 nuclease cuts specific sites.
3-9 months
Gene knockout, conditional knockout, gene knock-in, point mutation, humanization.
CRISPR/ Cas9
Cas9 nuclease cuts specific sites.
3-9 months
Gene knockout, conditional knockout, gene knock-in, point mutation, humanization.

Work Flow

What we provide/Our advantages

In-depth feasibility evaluation before your project starts

  • More rational model design to avoid artifactual phenotypes
  • More detailed project feasibility assessment
  • More accurate timelines

An efficient production line with rigorous quality control

  • Shortened project trunaround time
  • Guaranteed germline transmission of genetic modification in models generated from the ES cell targeting and CRISPR gene editing technologies

Regular and rigorous reporting during project implementation

  • A dedicated project manager
  • Seamless flow of information
  • One-on-one, face-to-face communication

A professional breeding support team and advanced animal breeding facilities

  • Animal health reports
  • Global delivery
  • Flexible delivery options
Email Back to top