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HBV-Tg

Background : B6.Cg

Catalog : NM-TG-00003

Strain Name :

B6.Cg-Tg(HBV)Smoc

Gene Summary

Gene Name

Synonyms :
Hepatitis B virus isolate C8, complete genome
NCBI ID :
AF461363
MGI ID :
Null
Ensembl ID :
Null
Strain State :
Repository Live

Model Description

Full-length HBV genome (adrsubtype,C genotype) was used to establish the transgenic mice. HBsAg was positive in transgenic mice serum; no serum HBeAg anti-HBs, anti-HBe, or antiHBc was detected. No anti-HBs or anti-HBe was detected in the polyethylene gly.

Validation Data

Fig1. Immuno-histochemical staining of HBsAg in the liver and kidney sections of #59 transgenic mice. Sections of liver (A) or kidney (B) tissues from #59 transgenic mice were stained for HBsAg.

Fig2. Immuno-histochemical staining of HBcAg in the liver and kidney sections of #59 transgenic mice.

Sections of liver (A) or kidney (B) tissues from #59 transgenic mice were stained for HBcAg.

Tab1. Eight Selected Genes From the Kidney of #59 Mice Assayed by Microarray and Real-Time PCR

Fig3. Dot blot immunoassay of complement C3 component in mouse serum and kidney tissue extract.

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