hCD80

Background : C57BL/6Smoc

Catalog : NM-HU-00074

Strain Name :

C57BL/6Smoc-Cd80em1(hCD80) Smoc

Gene Summary

Gene Name

Model Description

The endogenous mouse Cd80 gene was replaced by human CD80 gene .

Validation Data

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Fig1. Pattern of expression of CD80 over time on B cells, CD4+ and CD8+ T cells.  (Note: Splenocytes were activated by anti-mCD3/CD28 antibody.)

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Fig2. Expression characterization of hCD80 on activated B cells in Splenocytes in hCD80 KI mice.  (Note: Splenocytes were activated by anti-mCD3/CD28 antibody.)

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Fig3. Expression characterization of hCD80 on BMDM and BMDC in hCD80 KI mice. 

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