Home / Tnf-KO

Tnf-KO

Background : C57BL/6Smoc

Catalog : NM-KO-00100

Strain Name :

C57BL/6Smoc-Tnf^em1Smoc

Gene Summary

Gene Name

Exon2-3 of Tnf gene were targeted to generate the Tnf knockout mice.

Fig.1 Detection of TNF expression in spleen and thymus by RT-PCR.

Wild type: only one band at 209 bp with primers F1/R1(mTnf).

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

Fig.2 Detection of mTnf expression in spleen and thymus by Q-PCR.

Fig.3 Detection of mTNF-a expression in serum by ELISA (male, 8wks, n=2).

Abbr. HO, Homozygous; WT, wild type.

Note.TNF-KO and C57BL/6 mice were i.p. injected with LPS.