Trp53-KO

Background : B6.129

Catalog : NM-KO-00011

Strain Name : B6.129-Trp53tm1Smoc

Gene Summary

Gene Name

Model Description

A neo cassette replaces exons 2-11,including the start codon,of Trp53 (transformation related protein 53).Null homozygotes show high, early-onset tumor incidence;some have persistent hyaloid vasculature and cataracts.
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