Uox-Flox/Alb-Cre

Background : C57BL/6Smoc

Catalog : NM-XA-242357

Strain Name : C57BL/6Smoc-Uoxem1(flox)Tg(Alb-Cre)Smoc

Gene Summary

Gene Name
  • Strain State :

    活体

Model Description

The Uox-Flox was crossed with Alb-Cre to generate Uox-Flox/Alb-Cre mice.

Validation Data

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Fig 1. Effect of Allopurinol on Serum Uric Acid Levels. 6 week-old Uox-Flox/Alb-Cre male mice were Treated with Allopurinol. Compared to C57BL/6, serum uric acid levels of Uox-Flox/Alb-Cre male mice were significantly elevated. Treatment with allopurinol (100mg/kg) significantly reduced serum uric acid levels in Uox-Flox/Alb-Cre male mice (n=10). Values are expressed as mean ± SEM.

Abbr. WT, wild type.

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Fig 2. Body Weight Comparison. The body weight of Uox-Flox/Alb-Cre male mice was lower compared to C57BL/6 mice. Allopurinol treatment had no effect on body weight (n=10). Values are expressed as mean ± SEM. 

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Fig 3. Kidney Function Assessment. Kidney function in Uox-Flox/Alb-Cre male mice showed no significant difference compared to C57BL/6 mice (n=10). Values are expressed as mean ± SEM. 

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